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The synergistic effects of multiple signaling pathways can lead to systemic microcirculatory disorders, triggering various organ dysfunctions

doi: 10.1038/s41419-019-1678-y 43 LiXWangTXHuangXLiYSunTZangSet al

We further show how injected proteins Ip2 and Ip3 of T4 inhibit distinct subtypes of these Type IV REs

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Hence, glycolytic cells may be damaged by APAP likewise as mitochondria-dependent cells, however, due to their lower ROS levels, damaged mitochondria can be recycled via lysosomal autophagy and cells can recover (Fig