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Cell Tissue Res

This helps reduce unnecessary agitation and supports product integrity during laboratory use

J Pediatr 1986

We further mutated individual residues at the extracellular end of TM7 from E297 to I300 to proline and measured ghrelin-induced GHSR activation

The synthetic mRNA construct of claim 1, wherein the mRNA construct comprises 5' cap m7GpppGm, a 5' UTR of A1G AT1G58420 (SEQ ID NO: 10), a Kozak sequence (SEQ ID NO: 121), a coding sequence encoding human coagulation factor IX (F9), one 3' UTR of human alpha globin (hAG) (SEQ ID NO: 81), and a poly(A) tail

At the very least, immunogenicity would trigger the production of antibodies that neutralize the peptides effects