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Your body can store B12 in the liver for up to 4 years, which is why it can take years to know you have a deficiency within your diet and that your stores are depleted

The practical questions researchers ask are always the same: how much per day, and by what route

Within experimental models, it is commonly investigated for its interaction with peptide-mediated signalling networks and molecular mechanisms

It is normal

Symptoms of severe vitamin B12 deficiency can include visual disturbances, severe joint pain, paresthesia (tingling in the hands and feet), memory problems, depression, anxiety, poor muscle function, ataxia (impaired balance and coordination), changes in reflexes and even infertility

That said, oral supplements can vary