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Intermediate Metabolite During Energy Metabolism It is well known that glucose is considered the primary energy fuel, but during glucose depletion, such as during starvation, calorie restriction, and prolonged exercise, BHB, a major circulating ketone body, steps in as an energy source

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The introduction of a single His residue into human GSH transferase A1-1 created an unprecedented enzymatic function, suggesting a strategy that may be of broad applicability in the design of new enzymes

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