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[] Notably, high levels of MiDs lead to the recruitment of inactive DRP1, resulting in a hyperfused mitochondrial phenotype, [] while loss of MiD49/51 induces mitochondrial elongation

The only problem is most delivery methods to the hair get blocked by the scalp absorption barrier

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13,168 Diagnosis involves a comprehensive clinical evaluation, including detailed neurological examination, electrophysiological studies like NCS and electromyography (EMG) to assess motor and sensory fiber function and localize lesions, as well as imaging studies such as magnetic resonance imaging (MRI) to exclude compressive or structural causes

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Finally, the ongoing challenges for the clinical translation of NPPC-based therapies are discussed, along with potential directions for future research