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Weisel JW, Litvinov RI

2.3.5 Derivatives of reactive oxygen metabolites The concentration of derivates of reactive oxygen metabolites (dROM) was measured in triplicates using a colorimetric assay based on the method of Regenhard et al

This is further supported by Musaogullari, Mandato 64 , who demonstrated that oxidative stress-induced mitochondrial dysfunction enhances caspase-3 activation through the intrinsic apoptotic pathway

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Future work should unravel the biological pathways underlying peptide action to then identify specific metabolic pathways to which interventions for EIF recovery may target

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