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D., Codreanu, S

Happens to a very small percentage of people

Blocking lactate export by inhibiting the Myc target MCT1 Disables glycolysis and glutathione synthesis

APAP@PEG/HMnO 2 combined with ROS induced by cytotoxic benzoquinone metabolites and GSH depletion caused by HMnO 2 amplified the efficacy of chemotherapy by increasing intratumoral oxidative stress, leading to cell death in vitro as well as tumor suppression in vivo and increasing the survival rate [166]