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[29] However, oral formulations may have a combination of vitamin C, vitamin E, alpha-lipoic acid, N-acetyl cysteine, grape seed extract, etc

Environmental pollutants, inadequate sleep, and oxidative stress may also affect skin clarity and tone over time

J Heart Lung Transplant (2016) 35:96272

Additional information Edited by G Melino Supplementary Information accompanies this paper on Cell Death and Disease website Rights and permissions Cell Death and Disease is an open-access journal published by Nature Publishing Group