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For example, Khan et al

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reported that dietary iron overload in mice was able to induce hepatic macrophage M1 activation, and was also accompanied by hepatic fibrogenesis and steatohepatitis [64]

AK Voss and T Thomas have received research funding from the Cancer Therapeutics CRC (CTX)

On the one hand, these observations might be explained by the fact that an estrogen drop is required for the onset of ovulation 88 , and several flavoproteins (proteins using FMN and FAD as coenzyme) assist estrogen degradation by cytochrome P450 51,89 as they balance electrons from these reactions