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Based on these findings, the possible mechanisms of action of AGE on the process of neuroinflammation in A-induced AD have been proposed (51)

The tissues were homogenized (in a pool of 2 organisms) to 5% w/v in a Tris-HCl buffer in pH 7.6 in Tris-HCl buffer (50 mM Tris

10.1016/j.scitotenv.2014.12.064 32 CherkasovA

Nanoparticle (NP)-based systems enhance drug solubility and stability, improve pharmacokinetic profiles, facilitate passage across biological barriers, and enable targeted delivery to specific cells or tissues with surface modifications, thereby potentially increasing bioavailability while minimizing systemic toxicity

[DOI] [PubMed] [Google Scholar] 240.Xu Y., Wang Q., Dong M., Song H., Hang B., Sun Y., Zhang H., Hu J

The Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 Inhibits Lipopolysaccharide-Induced Osteoclast Formation and Bone Resorption via Inhibition of TNF-alpha Expression in Macrophages