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Those characterized by inhibitory (GABAergic) inputs may function as an incoherent FFL, acting to pulse activity, as illustrated by the transient inhibitory effects of the sst1 agonist at the synaptic GABAergic level (see Fig

Combined with the systemic immune modulation of thymosin alpha-1 and the cytokine reduction of KPV, a multi-peptide approach addresses both the root immune dysfunction and the resulting joint damage

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