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BSO-induced GSH depletion in CYP2E1-overexpressing HepG2 cells (E47 cells) activates NF-Kappa B and AP-1 [100]

Jung GW, Spencer EM, Lue TF

1.8 ml of phosphate buffer pH 8.0 was added to 0.1 ml of the supernatant and 0.1 ml of Ellman reagent

Nearly 50% of the patients and clinical investigators rated the therapeutic improvement as "good" or "fair," establishing 5-HTP as a viable option for managing these symptoms