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Similarly, lysosome associated protein transmembrane 4B (LAPTM4B) blocks ferroptosis by suppressing NEDD4L/ZRANB1-mediated ubiquitination and degradation of SLC7A11 (31)

In addition, several GSTs are reported to participate in auxin transport and auxin binding as non-substrate ligands

By comprehensively correcting disorders across multiple metabolite axes through dietary interventions (such as supplementing specific prebiotics and fibers), probiotic/postbiotic therapies, or small-molecule inhibitors (such as targeting microbial enzymes CutC/D to inhibit TMAO generation), it is expected that more fundamental and effective management of liver diseases can be achieved

This significantly increases liver sensitivity for growth hormone (LSG)

Genetic manipulation and developmental phenotype evaluation in S

Lactate: a metabolic key player in cancer