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Moreover, multi-targeted combination therapies that integrate synthetic and natural compounds could yield superior outcomes compared to single-target treatments

Olaparib has been studied for its neuroprotective effects in a mouse model of Huntingtons disease by modulating inflammasome activation 162

Decreased expression of GSH synthesis leads to low free GSH levels, resulting in elevated ROS, immune dysfunction, and increased disease severity in COVID-19 patients 592

The peptide category includes signal peptides (GHK-Cu, palmitoyl peptides), neurotransmitter inhibitors (Argireline / AH-8), and growth-factor analogs (sh-Oligopeptide-1)