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Theoharides TC, Cochrane DE

doi: 10.1038/cddis.2013.20 264 HarrisISTreloarAEInoueSSasakiMGorriniCLeeKCet al

Chronic Stress: High levels of cortisol (the stress hormone) can drain antioxidant reserves as the body attempts to manage the physiological impact of a busy lifestyle

Can animal study data be used as human guidance

927 These results suggest that HDAC3 maintains iron homeostasis through the Hippo/YAP pathway and might represent a target to reduce ferroptosis in iron overload-related diseases