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6, 15581562 doi: 10.1021/acsinfecdis.0c00288 54 Pujos-GuillotE.PickeringG.LyanB.DucheixG.Brandolini-BunlonM.GlomotF.et al

doi: 10.1016/j.bbrc.2022.01.106 201 MuriJ.KopfM

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Despite these conceptual advances, current microbiome profiling methodsoften based on 16S rRNA sequencingprovide limited functional resolution, and only a subset of studies incorporates shotgun metagenomics or metabolomics to directly link microbial shifts to host pathways, leaving important mechanistic questions unresolved (7, 8)

Endothelin-1 mediates the systemic and renal hemodynamic effects of GPR81 activation