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CDK4-mediated MnSOD activation and mitochondrial homeostasis in radioadaptive protection

Pott T, Bouvrais H, Mlard P

Bell et al., 2010

With a 65% probability threshold, ALADDIN showed a PPV and NPV of 79%, against FIB-4s 65% PPV and 80% NPV at a 2.66 threshold

Future research should focus on refining the mechanistic understanding of ferroptosis-HMGB1 interactions, particularly in relation to subcellular dynamics, post-translational modifications, and tissue-specific regulatory networks