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Finally, idiopathic pulmonary fibrosis (IPF) is a particularly aggressive and progressive ILD pathogenically based on an aberrant fibroproliferative wound healing response following multiple alveolar lesions, with a 5-yr survival of 30% 6,7

422 In SLE, the overexpression of CD38 impairs the PINK-Parkin pathway and disrupts mitophagy, leading to mitochondrial structural defects in SLE patients