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Why It Matters MMA builds up in your body when B12 levels are low because vitamin B12 is a critical cofactor in the biochemical pathway that converts methylmalonyl-CoA to succinyl-CoA

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Severe neurological effects, such as memory loss, disorientation, and impairments in motor skills, can result from a deficiency

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If youre taking vitamin B12 supplements in addition to the vitamin-rich foods youre consuming, you could experience diarrhea, nausea, vomiting and headache