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[12] Gastric acid-suppressing agents (proton-pump inhibitors and H-receptor antagonists) diminish dietary B12 liberation from protein complexes, a pharmacodynamic interaction that can exacerbate underlying deficiency

Nature 373 702705

Much more research is needed

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You should see LH moving toward the normal range (typically 1.7-8.6 IU/L) and testosterone beginning to recover

66 In 53 sheltered dogs exhibiting high anxiety levels, eating food with nearly four times more tryptophan than standard food for six weeks reduced abnormal social behaviors associated with stress