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It is especially beneficial for individuals who struggle with nutrient absorption or need more immediate improvements

Folic acid supplements are typically recommended to prevent or treat low blood folate levels

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Immediate allergic reactions are rare in the published literature, but delayed immunological effects have been documented in animals

Although we performed multivariate adjustments, residual confounding may persist due to unmeasured factors such as dietary habits (e.g., irregular intake of animal-derived foods or B12-fortified products), unrecorded use of nutritional supplements, and genetic predispositionsparticularly MTHFR polymorphisms, which are known to influence homocysteine metabolism and folate cycling, thereby potentially altering the functional demand for vitamin B12

Later, they are given monthly