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Nature 484, 546549

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Study models in endometrial research Limitations of classical endometrial study models Most reproduction studies in vivo rely on rodent models (mainly mice), which exhibit significant physiological differences compared to humans, in terms of cycle length (e.g

The lubricant coating on the needle degrades

However, the 7-day accumulation pattern means inconsistent dosing intervals may reduce steady-state stability and make it harder to distinguish between true lack of response and suboptimal pharmacokinetic timing

Under proper refrigeration, it maintains potency for approximately 4 to 6 weeks, though using it within 28 days is optimal