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Ethics declarations Ethics approval and consent to participate The ethical protocols for all animal experiments and methodologies were approved by the Animal Experimentation Ethics Committee of The Second Affiliated Hospital of Chongqing Medical University (IACUC-SAHCQMU-20230066)

Ingredients: Propylene, Glycol, Glycerin, Stearic Acid, Sodium Laureth Sulphate, Sodium Lauryl Sulphate, Elaeis Guineensis (Palm) Kernel Oil, Water, Sucrose, Sodium Hydroxide, Aloe Barbadensis (Aloe) Leaf Juice, Retinyl Palmitate, Sodium Ascorbyl Phosphate, Tocopheryl Acetate, Panthenol, Hydrolyzed Milk Protein, Lactose, Fragrance, Tetrasodium Etidronate, BHT, Limonene, Linalool, CI 42090, CI 19140.

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Cardiac-related referred pain : I20.0 for angina