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Laboratory research shows that milk thistle constituents inhibit uridine diphosphoglucuronosyl transferase (UGT), the major phase 2 enzyme that is responsible for glucuronidation

However, despite the discovery of anti-vimentin autoantibodies, other studies refuted that they could have a profound impact on the overall pathogenesis of the disease (99)

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8.2.3 Nutrients supporting mitochondrial biogenesis Compounds such as coenzyme Q10 (CoQ10), alpha-lipoic acid, and PGC-1 activators have been shown to promote mitochondrial biogenesis and improve mitochondrial function through various mechanisms