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Int J Mol Sci 25(14):7725 Chen L, Cao H, Huang Q, Xiao J, Teng H (2022) Absorption, metabolism and bioavailability of flavonoids: a review

Storage and Handling Requirements AOD-9604 typically arrives in lyophilized (freeze-dried) powder form that requires reconstitution before use

The drug will be exposed to stomach acid and liver metabolism (the first-pass effect), which can significantly break it down

Procrustes ANOVA identified a treatment effect on overall symmetrical shape differences in male and female offspring (p = 0.0013 and p = 0.0052, respectively)