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However, it is highly unlikely that the molecules exported via PGP pumps would reach the nervous system because the pumps are expressed on the apical domain of the intestine and will effectively transport molecules into the intestinal lumen 64

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doi: 10.1016/j.cmet.2015.07.006 53 MuraleedharanRGawaliMVTiwariDSukumaranAOatmanNAndersonJet al

Guaifenesin, the active ingredient in Mucinex, can cause dehydration-related dizziness and headaches because it works by thinning mucusdrinking 8+ glasses of water daily prevents these effects

major parasites ( in vitro and/or in vivo ) serve as prime candidates for future investigation into the discovery of antileishmanial compounds