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A phase 2 trial of TAS-102 with or without celecoxib in ctDNA-defined minimal residual disease (MRD) in colorectal cancer after completion of adjuvant chemotherapy

KEY WORDS : multidrug resistance, mechanisms of cell defense, P-glycoprotein, glutathione S-transferases, apoptosis, p53, Bcl-2 Abbreviations : MDR) multidrug resistance

17 BeatmanE

Emphasis is placed on emerging therapeutic avenues and innovative research directions

470 Diminished levels of taurine, along with aspartate, glycine, and gamma aminobutyric acid (GABA), have been noted in the brains of animals with experimentally-induced depression

Cells were then washed twice with PBS and fixed in 4% PFA (Fisher Scientific 50-980-494) in PBS containing 0.1% Triton X-100 (PBST, Sigma-Aldrich T9284) for 20 min at room temperature at dark