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Once the needle is injected, it releases liquid into your system, which can cause some pain

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doi:10.1056/NEJM196010132631504 9.RUBIN A, SPRITZ N, MEAD A, HERRMANN R, BRAVEMAN W, LUCKEY E

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Diet and exercise must be considered as the first line of treatment, however if they fail to correct metabolic signalling, IGF-1 therapy seems to be promising at metabolic harmonisation