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A recent systematic review showed that there was a malignant transformation rate of 0.1334% reported for oral leukoplakic lesions across 24 studies

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See: Statistics from Altmetric.com STRENGTHS AND LIMITATION OF THIS STUDY This was a large birth cohort study in Japan to investigate the risk and population attributable fraction of placental abruption associated with maternal smoking and secondhand smoke (SHS) exposure during pregnancy

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