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Research published in the American Journal of Respiratory and Critical Care Medicine (PMID: 31390877) has documented inflammatory responses in lung tissue after exposure to e-cigarette aerosol even from nicotine-free devices

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Dickison noted that he had received an inquiry regarding C8s possible toxicity. In 1961, just seven years later, in-house researchers already had the short answer to Dickisons question: C8 was indeed toxic and should be handled with extreme care, according to a report filed by plaintiffs