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USD 39.95 Prices may be subject to local taxes which are calculated during checkout Similar content being viewed by others Data availability The atomic coordinates for the CagriCTRG s and CagriAMY 1 RG s complexes have been deposited in the Protein Data Bank (PDB) under accession codes 9UWM and 9UWQ, respectively

Storage Requirements Lyophilized (Powder) Form: Store at 2-8C (refrigerated) for optimal stability Can be stored at room temperature (20-25C) for short periods Protect from light and moisture Shelf life typically 2-3 years when properly stored Cagrilintide 10mg should remain sealed until ready for reconstitution Reconstituted Solution: Store at 2-8C (refrigerated) immediately after reconstitution Use within 28 days of reconstitution Do not freeze Protect from light Discard if solution becomes cloudy or discolored Reconstitution Protocol Standard Reconstitution Steps: Prepare materials Cagrilintide vial, bacteriostatic water, alcohol swabs, syringes Clean vial tops Wipe both vials with alcohol swabs Draw bacteriostatic water Typically 2-4 mL depending on desired concentration Add to peptide vial Inject slowly down the side of the vial (not directly onto powder) Gentle mixing Swirl gently

REIMAGINE 3 was a 40-week efficacy and safety phase 3 trial of CagriSema 2.4 mg/2.4 mg and 1 mg/1 mg once-weekly versus placebo in 274 adults with type 2 diabetes as add-on to once-daily basal insulin with or without metformin

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