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Thiamine deficiency adversely affects the activity levels of these enzymes, with TK, through thiamine-dependent erythrocyte transketolase (ETK) activity, common biomarkers of thiamine status, since it is particularly sensitive to thiamine levels and AKD often exhibiting the earliest detectable changes (41)

The activation of IER3 in the mucosa downregulates Nrf2 through the PI3K/Akt pathway, leading to decreased ROS production and apoptosis in a colitis model, which keeps Nrf2 levels low in IBD (94)

Free radicals, metals and antioxidants in oxidative stress-induced cancer

Emerging neo adjuvants for harnessing therapeutic potential of M1 tumor associated macrophages (TAM) against solid tumors: Enusage of plasticity

To view a copy of this licence, visit About this article Cite this article Vyas, B., Bhowmik, R., Akhter, M

At the molecular level, L-Glutamine acts as a crucial nitrogen and carbon donor