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Funding: This study was supported by Grants-in-Aid for Young Scientists (A) (23689022) and Scientific Research on Innovative Areas (22133008) from the Ministry of Education, Culture, Sports, Science and Technology of Japan, and Grants-in-Aid from Takeda Science Foundation, SENSHIN Medical Research Foundation and Kowa Life Science Foundation

For these individuals, as well as those living with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and dysautonomia, exhaustion is not just feeling tiredit is a profound, cellular depletion of energy

Alpha-lipoic acid is unique among biological antioxidants

Accessed 1/8/2024, Baranwal N, Yu PK, Siegel NS

Regulating its production or signaling pathways provides a promising strategy for restoring immune metabolic balance and reducing intestinal inflammation

Briefly, for each condition, approximately 500 age-synchronized young adult (adult day 1) animals were collected in M9 buffer and washed three times to remove residual bacteria in the worm pellets