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AgelessRX is a longevity generalist

10.1016/j.neuro.2021.10.003 134 SongM

Nrf2, a redox-sensitive transcription factor, can be deacetylated and activated by SIRT1 and promotes the genes transcription of downstream detoxification enzymes and antioxidant enzymes [110, 111], such as SOD and HO-1[112-114]