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Metformin augments doxorubicin cytotoxicity in mammary carcinoma through activation of adenosine monophosphate protein kinase pathway

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As shown in Figure S11, the body weight of mice in the CDDP treatment group began to decrease on day 6, which might be caused by the side effect of injected CDDP on normal tissues of mice

Mol Pharmacol 2002

Unlike traditional treatments, which often have broad systemic effects, peptide therapy delivers targeted molecular messages right where theyre needed

Collection and processing of biological samples Venous blood was collected into ethylenediamine tetra-acetic acid (EDTA) tubes for plasma isolation and serum separator tubes for serum collection