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The authors of this work, in previous studies, have applied a systems biology approach to develop a methodology that enables the identification, aggregation, and integration of the signaling cascades at the cellular level to develop molecular systems architectures

61, S83S85

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Cell membrane-based nanoparticles: a new biomimetic platform for tumor diagnosis and treatment

Zheng M, Xu J, Feng Z

24 With respect to this, the negative association between frequency of the cSHMT -C1420T variant and latitude documented in this study may indicate that activity of the de novo thymidylate synthesis pathway is increasingly impaired in populations exposed to higher UVR, but the burden of this variant is unclear due to mSHMT likely maintaining cSHMT activity in such cases