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While genetics determine baseline melanin levels, lifestyle choices, sun protection, and a consistent skincare routine help manage and minimize pigmentation

Wu H, Ballantyne CM

These include shifts in the relative abundance of beneficial commensals, particularly those involved in short-chain fatty acid (SCFA) production, and an increase in pro-inflammatory or mucin-degrading taxa [35]

One regimen consists of daily injections of 1,000 mcg for one to two weeks, then a maintenance dose of 1,000 mcg every one to three months

Doctors choose hydroxocobalamin based on the patients needs and how they react to treatment

Consent for publication All participants included in this study provided written informed consent