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Additionally, SLC7A11-mediated cystine uptake induces metabolic vulnerabilities, including glucose and glutamine dependencies, creating potential therapeutic targets for inducing ferroptosis in cells by disrupting their redox balance and metabolic homeostasis (Yan et al., 2023)

Figure 30

Donaldson, L

Les consquences peuvent tre srieuses : l'organisme perd sa capacit liminer efficacement les dchets, son quilibre gnral se trouve fortement altr, et cela peut favoriser l'apparition de diverses pathologies