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Hepatocytes, the livers primary functional cells, contain ADH enzyme complexes that oxidize ethanol into acetaldehyde using NAD+ as an electron acceptor

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In Britain, the British National Formulary (BNF) recommends 1 mg IM OH-Cbl 3 times a week for 2 weeks and then maintenance 1 mg IM OH-Cbl every 3 months in patients without neurological involvement