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The biggest safety risk comes from using unregulated "research chemical" products rather than pharmaceutical-grade compounds from licensed pharmacies

10.1038/373702a0 Nature 195 UekiR.UchidaS.KandaN.YamadaN.UekiA.AkiyamaM.et al (2020)

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It can be legally purchased for research purposes in many regions

N-Acetylglucosamine 6-O-sulfotransferase-1 is required for brain keratan sulfate biosynthesis and glial scar formation after brain injury

Understanding their mechanistic distinctions is important for designing research protocols