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Physical exercise, cognition, and brain health in aging

While the re-establishment of blood flow is vital to salvage ischaemic tissue, it also triggers abrupt calcium influx into cardiomyocytes, which were already primed by ionic imbalances during ischaemia [12]

Lamprakopoulos, A., Zorzos, I

A number of drugs have oxidizing effects on cells and lead to production of oxygen radicals

Effects of L-carnitine on exercise tolerance in chronic stable angina: a multicenter, double-blind, randomized, placebo-controlled, crossover study

Consequently, this module is better defined as a collection of priority candidate pathways supported jointly by Level B and C evidence, useful for generating testable hypotheses and determining verification priorities, but not to be articulated as established causal mechanisms