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Description

The term basal ganglia classically refers to the caudate-putamen (also called the striatum) and the globus pallidus, whereas related nuclei consist of structures located in the subthalamus (the subthalamic nucleus, just above the tegmental area), the midbrain (the substantia nigra), and the pons (the pedunculopontine nucleus)

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2 In terms of biochemistry, it is mainly involved the increase of reactive oxygen species (ROS), decreased activity of glutathione peroxidase 4 (GPX4), iron disorder and accumulation of lipid peroxidation

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Glucoraphanin is the major glucosinolate associated with many health-benefits, as well as the prebiotic effects in broccoli

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Akbar R, Yam WK

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Haile Y, Deng X, Ortiz-Sandoval C, Tahbaz N, Janowicz A, Lu J-Q, Kerr BJ, Gutowski NJ et al (2017) Rab32 connects ER stress to mitochondrial defects in multiple sclerosis

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