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Description

Diabetes Care 2011, 34 (1), 162167

These metabolite-sensitive histone PTMs exemplify the interconnection of metabolism and epigenetic regulation 3,9,10

& Zhao, B

This paradoxical effect may be influenced by various factors, including the experimental methods and equipment used to detect mtROS, the type of cells affected, the duration of hypoxia, and the involved intracellular signaling mechanisms