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Moreover, robust evidence regarding long-term efficacy and cost-effectiveness, gaps in interdisciplinary collaboration, and challenges related to patient adherence and health equity collectively constrain the real-world applicability of this approach

To differentiate between the potential involvement of these two consequences in H 2 O 2 -induced sensitization to TNF hepatotoxicity, we first exposed HepG2 cells to (BSO), a potent inhibitor of gamma-glutamylcysteine synthetase, the rate-limiting enzyme in the glutathione synthesis pathway (Fig