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Multiple studies report elevated levels of LC3, p62, and Atg proteins, accompanied by reduced colocalization with lysosomal markers or delayed clearance of protein aggregates ( Substantial evidence supports mitochondrial dysfunction as a key mechanism in MPs/NPs neurotoxicity

Metab Brain Dis 36(8):23432357 Park HA, Broman K, Jonas EA (2021) Oxidative stress battles neuronal Bcl-xL in a fight to the death

Food 19, 11411146

A large retrospective analysis of more than 4,000 adults found that sublingual B12 raised blood B12 levels at least as effectively as intramuscular injections over the period studied (Bensky et al., 2019, DOI)

The depletion of GPX4 can increase the sensitivity of hepatocytes or cardiomyocytes to lipid peroxides, which can accelerate IRI-induced liver or cardiac injury [246,247,248]