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DOI: Published online: July 3, 2024 1 Department of Surgery, Yonsei University College of Medicine, Seoul, Korea 2 Department of Surgery, Ajou University School of Medicine, Suwon, Korea Correspondence: Hyoung Il Kim, Department of Surgery, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Korea Tel: 82-2-2228-2100 Fax: 82-2-313-8289 E-mail: [email protected] Received: March 29, 2024 Accepted: July 2, 2024 Copyright 2025 by the Korean Cancer Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

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As a result of the disarrayed F-actin at the luminal and basal ends of the cell, and the separation of occludin, ZO-1, and ZO-2 from the membrane of lateral TJs, C

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In vivo experiments indicated that it decreases ROS accumulation, inflammatory M1 macrophages, matrix degradation, and neovascularization, significantly improving IDD pathology