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Patients with severe, longstanding deficiency typically require longer recovery periods, with haematological improvement occurring over weeks and neurological recovery potentially taking months

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Novel therapeutic approaches have been tested in the last few years including new immunomodulatory drugs (IMiDs), proteasome inhibitors (PIs), and monoclonal antibodies (mAbs) [2, 3]

Your doctor also will review your medical history for medical illnesses (diabetes, immune disorders) or surgeries, such as stomach removal, that can lead to B 12 deficiency

Azcona C, Preece MA, Rose SJ, Fraser N, Rappaport R, Ranke MB, Savage MO

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