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The resulting crude product was purified by silica gel column chromatography (FL100D: EtOAc/MeOH = 6:1, Fuji Silysia Chemical, Kasugai, Japan) to give 51.1 mg (0.1978 mmol) of BME (94%)

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Iboshi Y, Nakamura K, Fukaura K, Iwasa T, Ogino H, Sumida Y, et al

These non-natural analogues stabilize mRNA and suppress innate immune activation, thereby enhancing therapeutic potency [27,28,29]

J Biol Chem 273: 52945299 Lee YJ, Galoforo SS, Sim JE, Ridnour LA, Choi J, Forman HJ, Corry PM, Spitz DR (2000) Dominantnegative Jun Nterminal protein kinase (JNK1) inhibits metabolic oxidative stress during glucose deprivation in a human breast carcinoma cell line

ARTICLE GHK-Cu modulates 4,000+ genes for younger skin