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Moreover, curcumin interferes with signaling cascades such as mitogen-activated protein kinases (MAPKs) and AP-1, and it can activate peroxisome proliferator-activated receptor-gamma (PPAR-), all of which further skew cells toward an anti-inflammatory phenotype ( In addition to dampening proinflammatory signals, curcumin modulates the immune response

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Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al

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Hillary Lin, MD Important clarification of where compounding, translational evidence, and online claims often diverge