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Nicotinamide (niacinamide) does not cause flushing and has fewer side effects, with nausea and liver toxicity reported only at very high intakes ~3 g/day)

Most people who eat non-vegetarian food meet their B12 needs

People of thiamin deficiency include those affected by: pregnancy chronic illness inadequate dietary intake alcoholism bariatric surgery chronic diuretic therapy Prolonged, untreated thiamin deficiency may lead to Wernicke-Korsakoff syndrome, a disorder that can affect people with chronic alcoholism, gastrointestinal disorders, or AIDS

Interestingly, we did not observe any relationships between LU median IC 50 values and Pfmdr1 N86Y during the study period

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Riboflavin (B2): Aids in energy production, metabolic processes, and supports antioxidant function